»Æ¹ÏÊÓÆµ

David Carl Brousseau, MD

Pediatrician in Chief & Chair of Pediatrics - DV

»Æ¹ÏÊÓÆµ Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803

Biography

Dr. Brousseau is board certified in Pediatric Emergency Medicine. His primary research focus is on sickle cell disease, including health services research, implementation science and clinical trials aimed at improving the disparate care these children receive.

Fellowship

  • Pediatric Emergency Medicine - Brown University at Hasbro Children's Hospital, 2000

Residency

  • General Pediatrics - Children's Hospital of Colorado, 1996

Education

  • M.S. - Brown University, 2000
  • M.D. - University of Virginia School of Medicine, 1993

Board Certifications

  • American Board of Pediatrics/Emergency Medicine

  • Emergency Medicine Utilization
  • Pediatric Emergency Medicine
  • Sickle Cell Disease

  • Acute Care Use Among People With Sickle Cell Disease, Sickle Cell Data Collection Program, 8 US States, 2018; Public Health Reports; (2025).

  • Associations Between Pain Scores and Opioid Doses With Emergency Department Disposition and Return Visit Rates in Children With Sickle Cell Disease; Pediatric Blood and Cancer; (2025).

  • Children with sickle cell disease and fever but no respiratory symptoms: Is a chest x-ray needed?; American Journal of Emergency Medicine; (2025).

  • Comparing Midline and Peripherally Inserted Central Catheters: A Randomized Feasibility Trial; Hospital Pediatrics; (2025).

  • Epidemiology, Intent, and Severity of Nonpowder Firearm Injuries in Patients Presenting to Pediatric Emergency Departments; Pediatric Emergency Care; (2025).

  • Evaluating the American Society of Hematology Quality Measure on Timeliness of Analgesics for Sickle Cell Disease Pain Crisis; Blood Advances; (2025).

  • Home Use of Nonpharmacologic Interventions For Fracture Pain After Pediatric Emergency Department Discharge; Journal of Emergency Medicine; (2025).

  • Hospital Variations in Time-To-Crisis-Resolution Among Children and Adolescents With Sickle Cell Disease; American Journal of Hematology; (2025).

  • Methodological progress note: Stepped-wedge cluster randomized trial design; Journal of Hospital Medicine; (2025).

  • Molecular inflammatory expression profiles associated with the frequency of pain in individuals with sickle cell disease; Blood Advances; (2025).

  • Opioid Timeliness in the Emergency Department and Hospitalizations for Acute Sickle Cell Pain; JAMA Pediatrics; (2025).

  • Timing of repeat epinephrine to inform paediatric anaphylaxis observation periods: a retrospective cohort study; Lancet Child and Adolescent Health; (2025).

  • Use of central venous access devices outside of the pediatric intensive care units; Pediatric Research; (2025).

  • Acute care utilization among individuals with sickle cell disease and related cardiopulmonary and renal complications; PLoS ONE; (2024).

  • Agreement of electronic health record–documented race and ethnicity with parental report; Academic Emergency Medicine; (2024).

  • Comparing Midline and Peripherally Inserted Central Catheters – a Randomized Feasibility Trial; medRxiv; (2024).

  • Health-Related Quality of Life for Parents of Infants with Bronchopulmonary Dysplasia; Journal of Pediatrics; (2024).

  • Inappropriate Use of Peripherally Inserted Central Catheters in Pediatrics: A Multisite Study; Hospital Pediatrics; (2024).

  • Timing of Repeat Epinephrine to Inform Anaphylaxis Observation Periods: A 31-Center Retrospective Cohort Study; SSRN; (2024).

  • A potential cost savings analysis of a penicillin de-labeling program.; Frontiers in allergy; (2023).

  • Intranasal fentanyl and discharge from the emergency department among children with sickle cell disease and vaso-occlusive pain: A multicenter pediatric emergency medicine perspective; American Journal of Hematology; (2023).

  • Multisite Oral Amoxicillin Challenges During Pediatric Emergency Department Visits.; JAMA pediatrics; (2023).

  • Return visit rates after an emergency department discharge for children with sickle cell pain episodes.; Pediatric blood & cancer; (2023).

  • Return visits after emergency department treatment for sickle cell pain crises.; American journal of hematology; (2023).

  • Sickle Cell Disease Treatment with Arginine Therapy (STArT): study protocol for a phase 3 randomized controlled trial.; Trials; (2023).

  • Adherence to NHLBI guidelines for the emergent management of vaso-occlusive episodes in children with sickle cell disease: A multicenter perspective; American Journal of Hematology; (2022).

  • Anaphylaxis knowledge gaps and future research priorities: A consensus report; Journal of Allergy and Clinical Immunology; (2022).

  • Detection of changes of functioning over time after asthma exacerbation in children with the use of PROMIS domains; Journal of Asthma; (2022).

  • Identification of Biological Processes Associated with Pain in Individuals with Sickle Cell Disease; US Association for the Study of Pain Annual Meeting; (2022).

  • Prospective Risk Stratification Identifies Healthcare Utilization Associated with Home Oxygen Therapy for Infants with Bronchopulmonary Dysplasia; Journal of Pediatrics; (2022).

  • Quality Improvement Project to Improve the Timeliness of Care for Children With Testicular Torsion in the Emergency Department; Pediatric Quality and Safety; (2022).

  • Understanding Influenza and SARS-CoV-2 Vaccine Hesitancy in Racial and Ethnic Minority Caregivers; Vaccines; (2022).

  • Understanding Vaccine Hesitancy, a Method to Improve COVID-19 and Influenza Vaccine Acceptance in Racial and Ethnic Minorities; Pediatric Academic Society Annual Meeting; (2022).

  • Updated Diagnosis Grouping System for Pediatric Emergency Department Visits.; Pediatric emergency care; (2022).

  • Validation of the Pediatric Sequential Organ Failure Assessment Score and Evaluation of Third International Consensus Definitions for Sepsis and Septic Shock Definitions in the Pediatric Emergency Department.; JAMA pediatrics; (2022).

  • Actual and Potential Impact of a Home Nasogastric Tube Feeding Program for Infants Whose Neonatal Intensive Care Unit Discharge Is Affected by Delayed Oral Feedings; Journal of Pediatrics; (2021).

  • Cephalosporin allergy symptoms in children presenting to a pediatric emergency department; Annals of Allergy, Asthma and Immunology; (2021).

  • Heart Disease, Advanced Age, Minority Race, and Hispanic Ethnicity Are Associated With Mortality in COVID-19 Patients.; WMJ : official publication of the State Medical Society of Wisconsin; (2021).

  • Heart disease, advanced age, minority race, and hispanic ethnicity are associated with mortality in covid-19 patients; Wisconsin Medical Journal; (2021).

  • PEMCRC anaphylaxis study protocol: A multicentre cohort study to derive and validate clinical decision models for the emergency department management of children with anaphylaxis; BMJ Open; (2021).

  • Severity grading system for acute allergic reactions: A multidisciplinary Delphi study; Journal of Allergy and Clinical Immunology; (2021).

  • A Multiyear Cross-sectional Study of Guideline Adherence for the Timeliness of Opioid Administration in Children With Sickle Cell Pain Crisis; Annals of Emergency Medicine; (2020).

  • Assessment of pediatric asthma exacerbation with the use of new PROMIS measures; Journal of Asthma; (2020).

  • Can PROMIS domains of pain and physical functioning detect changes in health over time for children with sickle cell disease?; Pediatric Blood and Cancer; (2020).

  • Correlates of sexually transmitted infection testing following women's release from jail: Correlates of STI testing following incarceration; Women and Health; (2020).

  • Home Oxygen Use and 1-Year Readmission among Infants Born Preterm with Bronchopulmonary Dysplasia Discharged from Children's Hospital Neonatal Intensive Care Units; Journal of Pediatrics; (2020).

  • Opioid Prescription Patterns at Emergency Department Discharge for Children with Fractures; Pain Medicine (United States); (2020).

  • Oral amoxicillin challenges in low-risk children during a pediatric emergency department visit; Journal of Allergy and Clinical Immunology: In Practice; (2020).

  • Persistent, refractory, and biphasic anaphylaxis: A multidisciplinary Delphi study; Journal of Allergy and Clinical Immunology; (2020).

  • Randomized Controlled Trial of Acute Illness Educational Intervention in the Pediatric Emergency Department: Written Versus Application-Based Education; Pediatric Emergency Care; (2020).

  • Teaching versus nonteaching hospitals: Where children with sickle cell disease receive their emergency department care; Journal of Pediatric Hematology/Oncology; (2020).

  • The association between timely opioid administration and hospitalization in children with sickle cell disease presenting to the emergency department in acute pain; Pediatric Blood and Cancer; (2020).

  • A Prospective Study of Parent Health-Related Quality of Life before and after Discharge from the Neonatal Intensive Care Unit; Journal of Pediatrics; (2019).

  • Hydroxyurea use for sickle cell disease among medicaid-enrolled children; Pediatrics; (2019).

  • Impact of Medical Scribes on Provider Efficiency in the Pediatric Emergency Department; Academic Emergency Medicine; (2019).

  • Improving emergency department management of diabetic ketoacidosis in children; Pediatrics; (2019).

  • Normal saline bolus use in pediatric emergency departments is associated with poorer pain control in children with sickle cell anemia and vaso-occlusive pain; American Journal of Hematology; (2019).

  • Parent Preferences Regarding Home Oxygen Use for Infants with Bronchopulmonary Dysplasia; Journal of Pediatrics; (2019).

  • Reported Knowledge and Management of Potential Penicillin Allergy in Children; Academic Pediatrics; (2019).

  • Seeking Care for Pediatric Illness: Health System Perspective; Academic Pediatrics; (2019).

  • Antibiotic use after removal of penicillin allergy label; Pediatrics; (2018).

  • Behavioral Changes in Children After Emergency Department Procedural Sedation; Academic Emergency Medicine; (2018).

  • Consensus-based Criterion Standard for the Identification of Pediatric Patients Who Need Emergency Medical Services Transport to a Hospital with Higher-level Pediatric Resources; Academic Emergency Medicine; (2018).

  • Health Information Preferences of Parents in a Pediatric Emergency Department; Clinical Pediatrics; (2018).

  • Parents' pain medication underdosing is associated with more emergency department visits in sickle cell disease; Pediatric Blood and Cancer; (2018).

  • Practice variation in emergency department management of children with sickle cell disease who present with fever; Pediatric Emergency Care; (2018).

  • Why Parents Seek Care for Acute Illness in the Clinic or the ED: The Role of Health Literacy; Academic Pediatrics; (2018).

  • Allergy testing in children with low-risk penicillin allergy symptoms; Pediatrics; (2017).

  • Association of guideline-adherent antibiotic treatment with readmission of children with sickle cell disease hospitalized with acute chest syndrome; JAMA Pediatrics; (2017).

  • Determining the longitudinal validity and meaningful differences in HRQL of the PedsQLâ„¢ Sickle Cell Disease Module; Health and Quality of Life Outcomes; (2017).

  • Impact of Chronic Conditions on Emergency Department Visits of Children Using Medicaid; Journal of Pediatrics; (2017).

  • Parent-Reported Penicillin Allergy Symptoms in the Pediatric Emergency Department; Academic Pediatrics; (2017).

  • Red blood cell transfusions during sickle cell anemia vaso-occlusive crises: a report from the magnesium in crisis (MAGiC) study; Transfusion; (2017).

  • Web-Based Surveillance of Illness in Childcare Centers; Health Security; (2017).

  • 2015 pediatric research priorities in prehospital care; Prehospital Emergency Care; (2016).

  • Impact of emergency department care on outcomes of acute pain events in children with sickle cell disease; American Journal of Hematology; (2016).

  • Multicenter Evaluation of Prehospital Opioid Pain Management in Injured Children; Prehospital Emergency Care; (2016).

  • Prehospital opioid administration in the emergency care of injured children; Prehospital Emergency Care; (2016).

  • The Benefits and Challenges of Preconsent in a Multisite, Pediatric Sickle Cell Intervention Trial; Pediatric Blood and Cancer; (2016).

  • What Parents Want: Does Provider Knowledge of Written Parental Expectations Improve Satisfaction in the Emergency Department?; Academic Pediatrics; (2016).

  • Which Febrile Children With Sickle Cell Disease Need a Chest X-Ray?; Academic Emergency Medicine; (2016).

  • A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children; Blood; (2015).

  • A randomized clinical trial of jet-injected lidocaine to reduce venipuncture pain for young children; Annals of Emergency Medicine; (2015).

  • Assessment of Food Insecurity in Children's Hospital of Wisconsin's Emergency Department.; WMJ : official publication of the State Medical Society of Wisconsin; (2015).

  • Assessment of food insecurity in children's hospital of wisconsin's emergency department; Wisconsin Medical Journal; (2015).

  • Association of care in a medical home and health care utilization among children with sickle cell disease; Journal of the National Medical Association; (2015).

  • Cost comparison of mechanically ventilated patients across the age span; Journal of Perinatology; (2015).

  • Health literacy affects likelihood of radiology testing in the pediatric emergency department; Journal of Pediatrics; (2015).

  • Prehospital Pediatric Care: Opportunities for Training, Treatment, and Research; Prehospital Emergency Care; (2015).

  • Psychosocial Care for Injured Children: Worldwide Survey among Hospital Emergency Department Staff.; The Journal of pediatrics; (2015).

  • The accuracy of using ICD-9-CM codes to determine genotype and fever status of patients with sickle cell disease; Pediatric Blood and Cancer; (2015).

  • The proportion of potentially preventable emergency department visits by patients with sickle cell disease; Journal of Pediatric Hematology/Oncology; (2015).

  • The use of the needle-free jet injection system with buffered lidocaine device does not change intravenous placement success in children in the emergency department; Academic Emergency Medicine; (2015).

  • Ambulatory quality indicators to prevent infection in sickle cell disease; American Journal of Hematology; (2014).

  • Caregiver low health literacy and nonurgent use of the pediatric emergency department for febrile illness; Academic pediatrics; (2014).

  • Emergency department and urgent care for children excluded from child care; Pediatrics; (2014).

  • Intravenous magnesium for pediatric sickle cell vaso-occlusive crisis: Methodological issues of a randomized controlled trial; Pediatric Blood and Cancer; (2014).

  • Lorazepam vs diazepam for pediatric status epilepticus: A randomized clinical trial; JAMA; (2014).

  • Low caregiver health literacy is associated with higher pediatric emergency department use and nonurgent visits; Academic Pediatrics; (2014).

  • Measuring health literacy in caregivers of children: A comparison of the Newest Vital Sign and S-TOFHLA; Clinical Pediatrics; (2014).

  • Sickle cell disease increases high mobility group box 1: A novel mechanism of inflammation; Blood; (2014).

  • Integration of the Medical College of Wisconsin Physician Scientist Pathway and Summer Research Programs to Increase Medical Student Research Skills; Medical Science Educator; (2013).

  • The relationship between parent health literacy and pediatric emergency department utilization: A systematic review; Academic Pediatrics; (2013).

  • Varying patterns of home oxygen use in infants at 23-43 weeks' gestation discharged from United States neonatal intensive care units; Journal of Pediatrics; (2013).

  • Concentration of hospital care for acute sickle cell disease-related visits; Pediatric Blood and Cancer; (2012).

  • Outpatient follow-up and rehospitalizations for sickle cell disease patients; Pediatric Blood and Cancer; (2012).

  • Self-report of child care directors regarding return-to-care; Pediatrics; (2012).

  • Associations between quality of primary care and health care use among children with special health care needs; Archives of Pediatrics and Adolescent Medicine; (2011).

  • Nonurgent emergency-department care: Analysis of parent and primary physician perspectives; Pediatrics; (2011).

  • Perceptions about water and increased use of bottled water in minority children; Archives of Pediatrics and Adolescent Medicine; (2011).

  • When children with sickle-cell disease become adults: Lack of outpatient care leads to increased use of the emergency department; American Journal of Hematology; (2011).

  • Acute care utilization and rehospitalizations for sickle cell disease; JAMA; (2010).

  • Emergency department reliance: A discriminatory measure of frequent emergency department users; Pediatrics; (2010).

  • In reply; JAMA; (2010).

  • The number of people with sickle-cell disease in the United States: National and state estimates; American Journal of Hematology; (2010).

  • Unnecessary child care exclusions in a state that endorses national exclusion guidelines; Pediatrics; (2010).

  • Vaso-occlusive painful events in sickle cell disease: Impact on child well-being; Pediatric Blood and Cancer; (2010).

  • A Randomized Clinical Trial of Ibuprofen Versus Acetaminophen With Codeine for Acute Pediatric Arm Fracture Pain; Annals of Emergency Medicine; (2009).

  • Dissatisfaction with hospital care for children with sickle cell disease not due only to race and chronic disease; Pediatric Blood and Cancer; (2009).

  • Postdischarge pain, functional limitations and impact on caregivers of children with sickle cell disease treated for painful events; British Journal of Haematology; (2009).

  • Primary Care Quality and Subsequent Emergency Department Utilization for Children in Wisconsin Medicaid; Academic Pediatrics; (2009).

  • Store-and-forward teledermatology versus in-person visits: A comparison in pediatric teledermatology clinic; Journal of the American Academy of Dermatology; (2009).

  • A prospective study of injury patterns in high school pole vaulters; American Journal of Sports Medicine; (2008).

  • Evaluation and Management of the Critically Ill Neonate in the Emergency Department; Clinical Pediatric Emergency Medicine; (2008).

  • Parental perception of quality of hospital care for children with sickle cell disease.; WMJ : official publication of the State Medical Society of Wisconsin; (2008).

  • Parental perception of quality of hospital care for children with sickle cell disease; Wisconsin Medical Journal; (2008).

  • Racial and ethnic disparities in nontraumatic dental-condition visits to emergency departments and physician offices : A study of the wisconsin medicaid program; Journal of the American Dental Association; (2008).

  • The effect of acute pain crisis on exhaled nitric oxide levels in children with sickle cell disease; Pediatric Blood and Cancer; (2008).

  • Urgency classification methods for emergency department visits: Do they measure up'; Pediatric Emergency Care; (2008).

  • Why Do Parents Bring Children to the Emergency Department for Nonurgent Conditions? A Qualitative Study; Ambulatory Pediatrics; (2008).

  • Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: Characterization of gene duplication events; Clinical Pharmacology and Therapeutics; (2007).

  • Quality of primary care and subsequent pediatric emergency department utilization; Pediatrics; (2007).

  • The Effect of CYP2D6 Polymorphisms on the Response to Pain Treatment for Pediatric Sickle Cell Pain Crisis; Journal of Pediatrics; (2007).

  • Categorizing Urgency of Infant Emergency Department Visits: Agreement between Criteria; Academic Emergency Medicine; (2006).

  • Emergency department allies: A controlled trial of two emergency department-based follow-up interventions to improve asthma outcomes in children; Pediatrics; (2006).

  • Methods of categorizing emergency department visit urgency: A survey of pediatric emergency medicine physicians; Pediatric Emergency Care; (2006).

  • Pain assessment for pediatric patients in the emergency department; Pediatrics; (2006).

  • The Impact of a Brief Expectation Survey on Parental Satisfaction in the Pediatric Emergency Department; Academic Emergency Medicine; (2006).

  • Acute idiopathic thrombocytopenic purpura of childhood - Diagnosis and therapy; Pediatric Emergency Care; (2005).

  • Association between parental and childhood emergency department utilization; Pediatrics; (2005).

  • Disparities for Latino children in the timely receipt of medical care; Ambulatory Pediatrics; (2005).

  • Emergency department wait times [12]; Pediatrics; (2005).

  • Intervention to improve interobserver agreement in the assessment of children with pharyngitis; Pediatric Emergency Care; (2005).

  • Variation in hospitalizations and hospital length of stay in children with vaso-occlusive crises in sickle cell disease; Pediatric Blood and Cancer; (2005).

  • Association between Infant Continuity of Care and Pediatric Emergency Department Utilization; Pediatrics; (2004).

  • The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations; Pediatric Emergency Care; (2004).

  • The effect of magnesium on length of stay for pediatric sickle cell pain crisis; Academic Emergency Medicine; (2004).

  • The Effect of Prior Interactions with a Primary Care Provider on Nonurgent Pediatric Emergency Department Use; Archives of Pediatrics and Adolescent Medicine; (2004).

  • Treatment of Pediatric Migraine Headaches: A Randomized, Double-Blind Trial of Prochlorperazine Versus Ketorolac; Annals of Emergency Medicine; (2004).

  • Validity and responsiveness of a brief, asthma-specific quality-of-life instrument in children with acute asthma; Annals of Allergy, Asthma and Immunology; (2004).

  • Pediatric emergency department utilization within a statewide medicaid managed care system.; Academic emergency medicine : official journal of the Society for Academic Emergency Medicine; (2002).

  • Pediatric emergency department utilization within a statewide Medicaid managed care system; Academic Emergency Medicine; (2002).

  • Higher-dose intravenous magnesium therapy for children with moderate to severe acute asthma; Archives of Pediatrics and Adolescent Medicine; (2000).